Disease Biology, Molecular Signaling & Developmental Biology Research

Our research focuses on exploring the different aspects of developmental biology using a model organism Caenorhabditis elegans (C. elegans) and novel factors that modulate cellular pathways, nano-mediated drug delivery and generate therapeutic strategies. Protein targeted approach towards Precision Cancer Therapeutics has been a newly added dimension of our research. We tend to model, and correct disease causing mutations leading to differential protein expression.

Prof. (Dr.) Jaya Bandyopadhyay


School of Biological Sciences and Technology

Department of Biotechnology
Maulana Abul Kalam Azad University of Technology, West Bengal

NH-12 (Old NH-34) Simhat
Haringhata, Nadia  741249, West Bengal
Phone: (033) 2589-1559

Room No. 033: Office (Biotechnology Building Ground Floor)

Lab No. 032: Molecular Development Lab

Lab No. 109: Tissue Culture Lab II & Cell Signalling Lab

Lab No. 119: Genetic Engineering Lab


Molecular Cell Biology
Genetic Engineering
Cell Signaling

Research Area

Cell Biology & Molecular Development
Precision Medicine in Cancer

About Prof (Dr.) Bandyopadhyay

Prof. (Dr.) Jaya Bandyopadhyay is a Professor of the Department of Biotechnology at Maulana Abul Kalam Azad University of Technology in West Bengal. With nearly 20 years of teaching experience, she has been associated with the department since its establishment in 2002. Her research interests include Cell Biology & Molecular Development, Nanoscience, Precision Medicine in Cancer, Neurotoxicology, and related subjects. She obtained her Ph.D. in 1995 from Visva Bharati University and pursued post-doctoral training in South Korea for over five years. She has also worked as a Visiting Scholar in Korean institutions and as a CSIR Senior Research Associate at the Indian Institute of Chemical Biology. Prof. Bandyopadhyay has supervised many students and has numerous publications and book chapters to her credit. In addition to her academic contributions, she has actively served in various administrative roles within the university.

Education & Professional Experience

Sl. No.Institution, PlaceDegree Awarded / PositionYearField of Study
1University of Calcutta, KolkataM.Sc.1990Zoology (Parasitology as Special Paper)
2Visva-Bharati University, Santiniketan, West BengalPh.D1995Zoology (Entomology & Ecology)
3Hormone Research Center, Chonnam National University, Gwangju, South KoreaPost-Doctoral Fellow1995-1998Postdoctoral research work in cell signaling using frog as the model system.
4Gwangju Institute of Science & Technology (GIST), Gwangju, South Korea.Post-Doctoral Fellow1998-2001Postdoctoral research experience in developmental genetics using C. elegans as the model system.
5Indian Institute of Chemical Biology (CSIR- IICB), Kolkata.Senior Research Associate (Scientist’s Pool Scheme)August 2001-October, 2002Postdoctoral research in the area of Molecular Physiology and Endocrinology on the mechanism of thyroid induced cardiac hypertrophy and molecular genetics of hypertrophic cardiomyopathy.

Position and Employment (Starting with the most recent employment)

Sl. No. Position held Duration

1.ProfessorJune 2020 – Present
2.Associate ProfessorAugust 2013 – June 2020
3.Assistant Professor (Selection Grade)August 2009 – August 2013
4.Senior Lecturer / Assistant ProfessorAugust 2005 – August 2009
5.LecturerOctober 04, 2002 – August 2005

Awards / Honors

1. Awarded the Shiksha Ratna 2022 for distinguished service for the cause of education conferred by the Government of West Bengal.

2. Awarded the Brain Pool Project-2007 funded by The Korean Federation of Science and Technology Societies (KOFST) and worked as a Visiting Scholar for 1 year (April, 2007~ March, 2008) in Gwangju Institute of Science & Technology (GIST), Gwangju, South Korea and and Hanyang University, Seoul, South Korea.

3. Awarded Travel Grant by DST (Govt. of India) to attend the 1st International Conference on Model Hosts, Heraklion, Crete, Greece, Sep 05-Sep 10, 2010.

Present Research Activities

Will be updated soon.

Research Collaborators (National)

Dr. Saikat Chakrabarti, Senior Principal Scientist & Deputy Head, Structural Biology & Bioinformatics Division, CSIR-Indian Institute of Chemical Biology, Kolkata.

Prof. (Dr.) Debashis De (Professor, CSE Department, MAKAUT,WB).

Dr. Soumalee Basu, Assistant Professor, Dept. of Microbiology, University of Calcutta, Kolkata.

Prof. (Dr.) Angsuman Sarkar, Professor, Department of Electronics & Communication Engg, Kalyani Govt. Engg. College, Kalyani.

Prof. Pintu Sen, Scientific Officer H, Professor, Homi Bhabha National Institute, Variable Energy Cyclotron Centre, 1/AF, Bidhan Nagar, Kolkata – 700 064, India.

Dr Dambarudhar Mohanta, Associate Professor, Department of Physics, Tezpur University, Assam.

Prof. Tarun Kanti Bhattacharya, Dept of Electronics & Electrical Communication Engg., Advanced Technology Development Centre, Prof-in-charge, Advanced VLSI Laboratory National MEMS Design Centre, IIT Kharagpur, West Bengal, India.

Dr. Samir Chandra Das, System Manager, Centre for Research in Nanoscience and Nanotechnology (CRNN), University of Calcutta, JD-2, Salt Lake City, Kolkata 700098, West Bengal, India.

Dr. Partha Pratim Parui, Department of Chemistry, Jadavpur University, West Bengal, India.

Research Collaborators (International)

Prof. Joohong Ahnn, Department of Life Science, Hanyang University with Department of Biotechnology, MAKAUT, W.B.

Post-Doctoral Fellow (Former)

Dr. Susmita Roy (DST N-PDF): Broad area of research: Immunomodulatory roles of candidate genes in Down syndrome patients giving special emphasis to T cell activation.

Senior Research Assistant (Former)

Mr. Sudhanshu Mishra, M.Tech (Project Name: Investigation of the activity of graphene and its derivatives towards the biological systems with special relevance to C. elegans.).

Membership in Scientific Bodies

1. Life Member of the Society for Biological Chemists (India).

2. Former Member of the Genetics Society of America.

Invited Talk (Foreign)

Participation as plenary speaker – First International Conference and Exhibition of Organisation for Women in Science for the Developing World (OWSD). Conference Date: 3-6 June, 2013; Venue: Elf Lecture Theater, Main Campus, University of Uyo, Uyo, Akwa Ibom State, Nigeria. Title of the paper: Caenorhabditis elegans as a model organism to study sterol transport and metabolism in development: Implications for Peptidyl prolyl cis-trans isomerase 1 (Pin-1) as a negative modulator.

Nramp-like Metal Transporters in C. elegans: a model for studying Mn-mediated innate immunity. J Bandyopadhyay*, J Ahnn, and JH Cho. 2010. 1st International Conference on Model Hosts, Heraklion, Crete, Greece, Sep 05-Sep 10, 2010.

Role of Calcium Binding Proteins in Multiple Aspects of Behavior in Caenorhabditis elegans. Jaya Bandyopadhyay* and Joohong Ahnn. Invited talk at “The 7th International Symposium on Developmental Biotechnology, October 26-27, 2007, Jeju University, Jeju, South Korea.”

Cloning and Characterization of cDNA Encoding Rana P34CDC2 kinase, A component of the Maturation Promoting Factor. Jaya Bandyopadhyay*, Arun Bandyopadhyay, Hae-Mook Kang, Heung-Sik Choi and Hyuk Bang Kwon. 1998. Invited talk at The Third International Symposium for Asia and Oceania Society for Comparative Endocrinology Kwangju, Republic of Korea, September 22-25 (1998).

Invited Talk / Key note Address / Chairing Sessions (selected) (National)

Caenorhabditis elegans, an emerging animal model for biosensing studies. Invited talk at the CCSN2018: 7th International Conference on Computing, Communication and Sensor Network, held at Biswa Bangla Convention Centre on 27th – 28th October, 2018; Session: “Biotechnology and Image Sensing”.

Chaired the session at The Second Indian C. elegans meeting, 2018 at NII, New Delhi during 23rd – 26th February, 2018 on Neuronal Trafficking and Protein Aggregation.

C. elegans and Biogerontology: A Genetic Dissection to the Mechanism of Aging. Invited Resource person for Refresher Course in Life Sciences (thrust area: Challenges and options in Life Science Research in the developing world today) for college and university teachers during Dec. 23, 2016 – Jan.13, 2017.

Analysing C. elegans behaviour as a parameter for treated water quality Testing: Invited talk at the Advanced Workshop on Microbial Technology for Clean Environment. Jointly Organized by COEETM, MAKAUT, WB and Tripura University, 18th to 21st September, 2017.

Chaired the session at The First Indian C. elegans meeting, 2016 at the 40th Mahabaleshwar Seminar during 30th January – 02nd February, 2016 on Molecules to Circuitry.

Scope of Biotechnology in Food Processing and Food Safety: Recent Advances and the West Bengal Scenario. Invited talk at the Seminar on PROMOTION OF FOOD PROCESSING INDUSTRIES IN WEST BENGAL; Focus on Planning, New Technologies, Marketing Strategies; Sponsored by ICC & Department of Food Processing Industries & Horticulture, Government of West Bengal; 17th October 2012, Royal Bengal Room, City Center 1, Salt Lake, Kolkata

Oxidative stress alters gene expression in human neuroblastoma cells. 2010. Invited talk at the 17th State Science & Technology Congress, Kolkata, March 4-5, Abstract BT19,Page 386.

Invited speaker in a Workshop on Bioinformatics at Haldia Institute of Technology, Haldia (20-21 March, 2007) at the Department of Computer Science & Informatics, HIT, WB.

Papers presented at Conferences by Research Scholars

Sohini Kulavi1, Debajit Dhar1, Izaz Monir Kamal2, Saikat Chakrabarti2, and Jaya Bandyopadhyay1. 2023. Analysis of EIF4A3 Network in Glioma and Virtual Screening of Natural Inhibitors from Medicinal Plants with Anti-Glioma Activity. Poster presented and has been awarded 1st Prize for the Poster Presentation in the 8th Annual International Conference under the theme “Genetics & Genomics in Health and Diseases” of the Board of Genetic Counseling, India & University of Hyderabad held from 7th-9th July 2023 at Hyderabad, India.

Sohini Kulavi1*, Debajit Dhar1, Izaz Monir Kamal2, Saikat Chakrabarti2 and Jaya Bandyopadhyay1 . 2022. Protein Targeted Phytotherapy for Glioblastoma: An Initiative towards Precision Medicine. Poster presented in the 91ST ANNUAL MEETING OF THE SOCIETY OF BIOLOGICAL CHEMISTS, INDIA, held from 8 to 11 December 2022 in Kolkata, India.

Sohini Kulavi1*, Debajit Dhar1, Izaz Monir Kamal2, Shubham Saini1, Saikat Chakrabarti2 and Jaya Bandyopadhyay1 . 2022. Protein Specific Therapeutic Intervention in Glioblastoma Multiforme Using Bioactive Compounds from Castanea sativa and Withania somnifera – An Integration of Phytotherapy into Precision Onco-medicine. Poster presented in the ADVANCES IN MOLECULAR DIAGNOSTICS AND PRECISION MEDICINE in association with Cancercon 2022 held from 15-17 September 2022 at Anna University, Chennai, India.

Tanaya Paul*, Kunal Biswas, Sudhanshu Mishra, Swati Sinha and Jaya Bandyopadhyay. 2018. Thermo-chemical micro-sensing system of a biological model organism C. elegans towards a chemical stimulus. Paper presented in 7th International Conference on ‘Computing, Communication and Sensor Networks’, CCSN2018. (https://ccsnmicro.wixsite.com/ccsn2018).

Kunal Biswas*, Tanaya Paul, Sudhanshu Mishra, Arghajit Biswas, Debashis De, and Jaya Bandyopadhyay. 2018. Single Layer Graphene Oxide (SLGO) nanosheet exhibited reduced altered locomotion, survivability and differential behavioral response compared to multilayered Graphene Oxide (GO) nanosheets in eukaryotic model C. elegans. Poster presentation at The Second Indian C. elegans meeting, 2018 at NII, New Delhi during 23rd – 26th February, 2018.

Tanaya Paul*, Nayan Pandey and Jaya Bandyopadhyay. 2018. Effects of 2-(ethylhexyl) phthalate in C. elegans on reducing health span, pharyngeal pumping and induction of ROS generation. Poster presentation at The Second Indian C. elegans meeting, 2018 at NII, New Delhi during 23rd – 26th February, 2018.

Extramural Research Grants

Sl. No.TitleAgencyPeriodGrant / Amount (Rs. in lakhs)
1Investigation of the activity of graphene and its derivatives towards the biological systems with special relevance to C. elegans.(As PI)Department of Higher Education, Science and Technology and Biotechnology, Government of West Bengal2019-202222.66
2A Functional Study On Peptidyl Prolyl Cis/Trans Isomerase Pin1 Homologue In Caenorhabditis elegans.(As PI)CSIR2011-201419.5
Molecular Mechanism of Thyroid hormone-induced Oxidative stress and Hypoxia in neuroblastomas: Identification of Differentially Expressed Genes by cDNA Array Analysis(As PI)
4Isolation, biological properties and explorations of lectin–quantum dot nano conjugates as novel fluorescent marker for identification of cancer cells. (As Co-PI)CSIR2010-201423.416
5Anti-amyloidogenic effects of some antioxidant phytochemicals present in common traditional plant: Implications for the prevention and therapeutics of Alzheimer’s Disease (AD). (As Co-PI)Department of Science & Technology, Govt. of West Bengal2011- 201412.38

Identification of novel BACE-1 inhibitors by simulating BACE1-flavonoid interaction to identify new pharmacophore model followed by virtual screening in 3-D ligand database – a de novo drug design approach.(As Co-PI)Department of Science & Technology, Govt. of India
7In vitro studies of some Homeopathic drugs medicines on the proliferation and differentiation of neural stem cells.(As Co-PI)Central Council for Research in Homoeopathy (CCRH)2012-201526.06