Bandyopadhyay Lab

Research Interest:

Cancer therapeutics, Precision herbal medicine & Computer aided drug discovery.

Recent Research Activites:

• Sohini Kulavi¹, Debajit Dhar¹, Izaz Monir Kamal², Saikat Chakrabarti², and Jaya Bandyopadhyay¹. 2024. Precision Targeting of EIF4A3 in Glioblastoma with Phytochemicals from Indian Medicinal Plant: An In Silico Approach Integrating Phytotherapy into Oncology. Oral Presentation in the National seminar on “Trends in Biomedical Research: Advances and Challenges” held from 29th-30th January, 2024 at CCRAS-Central Ayurveda Research Institute, Kolkata.
• Sohini Kulavi¹, Debajit Dhar¹, Izaz Monir Kamal², Saikat Chakrabarti², and Jaya Bandyopadhyay¹. 2023. Analysis of EIF4A3 Network in Glioma and Virtual Screening of Natural Inhibitors from Medicinal Plants with Anti-Glioma Activity. Poster presented and awarded 1st Prize for the Poster Presentation in the 8th Annual International Conference under the theme “Genetics & Genomics in Health and Diseases” of the Board of Genetic Counseling, India & University of Hyderabad held from 7th-9th July 2023 at Hyderabad, India.
• Sohini Kulavi^1*, Debajit Dhar¹, Izaz Monir Kamal², Saikat Chakrabarti² and Jaya Bandyopadhyay¹ . 2022. Protein Targeted Phytotherapy for Glioblastoma: An Initiative towards Precision Medicine. Poster presented in the 91ST ANNUAL MEETING OF THE SOCIETY OF BIOLOGICAL CHEMISTS, INDIA, held from 8 to 11 December 2022 in Kolkata, India.
• Sohini Kulavi^1*, Debajit Dhar¹, Izaz Monir Kamal², Shubham Saini¹, Saikat Chakrabarti² and Jaya Bandyopadhyay¹ . 2022. Protein Specific Therapeutic Intervention in Glioblastoma Multiforme Using Bioactive Compounds from Castanea sativa and Withania somnifera – An Integration of Phytotherapy into Precision Onco-medicine. Poster presented in the ADVANCES IN MOLECULAR DIAGNOSTICS AND PRECISION MEDICINE in association with Cancercon 2022 held from 15-17 September 2022 at Anna University, Chennai, India.

Past Research Experience:

• Summer Research Fellowship Program 2017 Indian Science Academies (IAS, INSA, NASI); Title: In silico analysis of differential expression of miRNA and its target prediction using non-coding RNA-Seq dataset; Guide: Dr Dinesh Gupta, International Centre for Genetic Engineering and Biotechnology, New Delhi.
• Summer Training 2018; Title: Zinc oxide (ZnO) nanoparticles mediated targeted delivery of Curcumin to cancer cells; Guide: Dr Parames Chandra Sil; Bose Institute, Kolkata, West Bengal.
• Summer School of IASc-INSA-NASI Focus Area Science Technology Summer Fellowship [FAST-SF] – 2019 on ‘Science of Materials’ organized by UM-DAE Centre for Excellence in Basic Sciences, University of Mumbai, Kalina Campus (May 6- June 14, 2019).
• B.Tech Project. Project Title: Green Synthesis of Quercetin Conjugated AuNPs using Citrus Lemon Extract as a Best Alternative to Trisodium Citrate and a Comparative Study based on their Characterization and Antibacterial and Anti-cancer Activity. Duration: 1-year Guide: Dr. Sirshendu Chatterjee, Techno India University, West Bengal, India
• M.Tech Thesis. Project Title: Exploring the Possibilities of CNT-Mediated Management of Alzheimer’s disease in C. elegans through a Comprehensive Review. Duration: 6 months Guide: Dr. Jaya Bandyopadhyay, Maulana Abul Kalam Azad University of Technology, West Bengal, India.

Hobbies:

Music, Painting, Movie.

Publications

• Sohini Kulavi, Debajit Dhar, Karan Iyer, Arnab Kumar Ghosh and Jaya Bandyopadhyay* (2024). Unveiling the Potentials of Withania somnifera (L.) Dunal as a Precise Therapeutic Intervention Against Glioblastoma Multiforme. © International Academic Publishing House (IAPH), Dr. Somnath Das, Dr. Ashis Kumar Panigrahi, Prof. Rose Stiffin and Dr. Jayata Kumar Das (eds.), Life as Basic Science: An Overview and Prospects for the Future Volume: 1, pp. 68-91. ISBN: 978-81-969828-9-8 doi: https://doi.org/10.52756/lbsopf.2024.e01.007
• Kulavi S, Dhar D, Kamal IM, Chakrabarti S, Bandyopadhyay J. EIF4A3 targeted therapeutic intervention in glioblastoma multiforme using phytochemicals from Indian medicinal plants–an integration of phytotherapy into precision onco-medicine. Journal of Biomolecular Structure and Dynamics. 2024 Feb 2:1-21.
• Iyer K, Saini S, Bhadra S, Kulavi S, Bandyopadhyay J. Precision Medicine Advancements in Glioblastoma: A Systematic Review. BioMedicine. 2023;13(2):1.
• Kulavi S, Kaur R, Iyer K, Bandyopadhyay J, Sengupta T. A smart & precise approach with nanoparticles-based therapeutic intervention in neurodegenerative diseases. Nanomedicine Journal. 2023 Apr 1;10(2).
• Ghosh C, Saha M, Kulavi S, Chatterjee S. In-silico Screening of Some Important Bioactive Compounds as Potential Inhibitors of 3CLpro Protein of SARS-CoV-2 and MERS-CoV Virus. International Journal of Pharmaceutical Sciences and Nanotechnology (IJPSN). 2022 Sep 15;15(4):6043-54.
• Kulavi S, Chatterjee S, Ghosh C, Saha M. A Compendium of Precision Oncology: An Approach towards Unveiling the Unique and Individualized Reality of Cancer. Current Aspects in Pharmaceutical Research and Development Vol. 6. 2021 Dec 6:21-43.
• Kulavi S, Banerjee S, Sengupta T, Ghosh C, Saha M, Chatterjee S. Virtual screening through molecular docking analysis to identify potential natural inhibitor (s) of Lyn tyrosine kinase-an in-silico approach. Journal of Pharmaceutical Research International. 2021 Nov 15;33(50A):85-105.
• Sohini Kulavi¹, Subhadra Nandi¹, Chandrima Das¹, Titav Sengupta¹, Moumita Saha¹, Chandreyi Ghosh¹, Pranabesh Ghosh¹, Arpita Saha² and Sirshendu Chatterjee¹; Characterization and Comparative Evaluation of Antibacterial and Cytotoxic Efficacy between two Quercetin-Au- Nanoconjugates synthesized using Pure Tri-Sodium Citrate and its Natural Alternative – Lemon Extract. Int. J. Res. Ayurveda Pharm. 2021;12(2):33-41 http://dx.doi.org/10.7897/2277- 4343.120242
• Kulavi S, Ghosh C, Saha M, Chatterjee S. One Size Does Not Fit All: An Overview of Personalized Treatment in Cancer. Journal of Pharmaceutical Research International. 2021:87-103.
• Chatterjee S, Das S, Ghosh P, Sengupta T, Nandi S, Kulavi S, Mandal S. Green Synthesis of Silver Nanoparticles Using Olden-landia corymbosa and Ocimum sanctum Leaf Aqueous Extract. International Journal of Pharmaceutical Sciences and Nanotechnology (IJPSN). 2020 Nov 23;13(3):4959-64.
• Chatterjee S, Saha M, Ghosh P, Nandi S, Sengupta T, Sohini Kulavi, Das S. Green synthesis and characterization of silver nano-conjugates using some common medicinal weeds leaf aqueous extracts. International Journal of Pharmaceutical Sciences and Nanotechnology (IJPSN). 2020 Jan 31;13(1):4752-8.
• Ghosh P, Kulavi S, Nandi S, Sengupta T, Biswas M, Das P, Das C, Chatterjee S. Green synthesis and characterization silver nano-conjugates using Heliotropium indicum and Glycosmis pentaphylla leaf aqueous extracts. Journal of Nanoscience, Nanoengineering & Applications. 2019;9(2):22-30.

Achievements

1. Awarded 1st Prize for the Poster Presentation in the 8th Annual International Conference under the theme “Genetics & Genomics in Health and Diseases” of the Board of Genetic Counseling, India & University of Hyderabad held from 7th-9th July 2023 at Hyderabad, India.
2. University (in-house) 2^nd rank holder in M.Tech Biotechnology Degree Program (Batch 2019-2021).
3. Awarded the Best Poster Award in National Seminar on New Horizons in Biotechnology conducted by Department of Biotechnology, Haldia Institute of Technology, West Bengal on 21st September 2019.
4. Secured 3^rd rank (Bronze Medalist) in University, in the stream of B.Tech Biotechnology Degree Program (Batch 2015-2019)
5. Selected for the Summer Research Fellowship Program 2017 organized by the Indian Science Academies (IASc, INSA, NASI).Selected and participated in the International Conference IABS 2018 (An Interdisciplinary Approach to Biological Sciences) for Poster Presentation at the Indian Association of Cultivation of Science, Kolkata, India.
6. Selected and participated in the 3^rd Regional Science and Technology Congress in 2018 and 4^th Regional Science and Technology Congress in 2019.Selected as one of the top three in the five-day workshop on “Molecular Cloning: The Know how” by Dr. KPC Life Sciences Pvt. Ltd in 2019.
7. Summer School of IASc-INSA-NASI Focus Area Science Technology Summer Fellowship [FAST-SF] – 2019 on ‘Science of Materials’.